With reference to normal human beings, consider the following statements:1. In response to the presence of HCl, secretin is produced from the duodenum.2. Enterogastrone is produced in the small intestine in response to the presence of fatty acids. Which of these statements is/are correct?
✓ Correct answer: c) Both 1 and 2
ExplanationStatement 1 is correct: When hydrochloric acid (HCl) from the stomach enters the duodenum, it lowers the pH of intestinal contents.This triggers S-cells in the duodenal lining to release secretin.Secretin signals the pancreas to release bicarbonate-rich fluid.This fluid neutralizes the acid, creating an optimal environment for digestive enzymes to function.Statement 2 is correct: Enterogastrone refers to a group of hormones secreted by the duodenal mucosa when dietary fats are present.These hormones, including secretin and cholecystokinin (CCK) slows down gastric motility and inhibit stomach secretions.This regulation ensures that chyme moves gradually from the stomach to the small intestine, promoting better fat digestion and absorption.454
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