🔬 Science & TechnologyUPSC 2019Space & Space Technology

What is Cas9 protein that is often mentioned in the news?

aA molecular scissors used in targeted gene editing
bA biosensor used in the accurate detection of pathogens in patients
cA gene that makes plants pest-resistant
dA herbicidal substance synthesized in genetically modified crops
✓ Correct answer: a) A molecular scissors used in targeted gene editing
ExplanationThe Cas9 protein, often referred to as “molecular scissors,” is an enzyme utilized in targeted gene editing.It originates from the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) system, which serves as an adaptive immune mechanism in bacteria.Guided by a specific RNA sequence, Cas9 binds to a complementary DNA sequence and introduces a double-stranded break.This break facilitates targeted modifications, such as gene insertion, deletion, or correction.Cas9 has revolutionized genetic research and therapy by enabling precise edits in the genomes of various organisms, including plants, animals, and humans.This technology holds potential for treating genetic disorders, developing disease-resistant crops, and advancing gene therapy.53

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