🔬 Science & TechnologyUPSC 2019Space & Space Technology

Which of the following are the reasons for the occurrence of multi-drug resistance in microbial pathogens in India?1. Genetic predisposition of some people2. Taking incorrect doses of antibiotics to cure diseases3. Using antibiotics in livestock farming4. Multiple chronic diseases in some peopleSelect the correct answer using the code given below.

a1 and 2
b2 and 3 only
c1, 3 and 4
d2, 3 and 4
✓ Correct answer: b) 2 and 3 only
ExplanationAntimicrobial Resistance (AMR) is the ability of microorganisms like bacteria, viruses, fungi, and parasites to resist the effects of antimicrobial drugs, making infections harder to treat.When microorganisms such as bacteria develop resistance to multiple drugs, it is specifically termed Multidrug Resistance (MDR), posing a serious challenge to effective treatment.Statement 1 is incorrect: Multi-drug resistance is primarily a result of microbial adaptation, excessive antibiotic use, and misuse rather than human genetic predisposition.Genetic predisposition is a genetic trait that, in response to environmental factors, may influence the potential phenotypic development of an individual organism within a species or community.Antibiotic resistance is not related to the genetic tendency of a small minority of persons in a society.Statement 2 is correct: Misuse of antibiotics, such as incorrect dosing, premature discontinuation of prescribed antibiotics, or self-medication, allows bacteria to survive and develop resistance.WHO mentions inappropriate use of antibiotics as a major dr

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