With reference to recent developments regarding ‘Recombinant Vector Vaccine’, consider the following statements:1. Genetic engineering is applied in the development of these vaccines.2. Bacteria and viruses are used as vectors.Which of the statements given above is/are correct?
✓ Correct answer: c) Both 1 and 2
ExplanationA Recombinant Vector Vaccine is a vaccine that uses a genetically modified virus or bacterium as a carrier to deliver pathogen-specific genes, triggering an immune response.Statement 1 is correct: Recombinant vector vaccines are developed using genetic engineering to insert genes encoding antigens into harmless viruses or bacteria, which serve as vectors.These vectors deliver the genetic material into the body, enabling the expression of target antigens and triggering an immune response against the pathogen.Examples include viral vector vaccines like Oxford-AstraZeneca (ChAdOx1 nCoV-19) and Sputnik V for COVID-19. Statement 2 is correct: Both bacteria (such as Salmonella) and viruses (such as adenoviruses and vesicular stomatitis virus) can be used as vectors to deliver genetic material into host cells to stimulate an immune response.50
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