Consider the following statements: 1. Genetic changes can be introduced in the cells that produce eggs or sperms of a prospective parent. 2. A person’s genome can be edited before birth at the early embryonic stage. 3. Human induced pluripotent stem cells can be injected into the embryo of a pig. Which of the statements given above is/are correct?

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Correct answer: 1, 2 and 3. Gene therapy is the ability to improve genes through the correction of misplaced (mutated) genes or site-specific alterations with therapeutic treatment as the target. A gene abnormality that has been identified in a child or embryo can be corrected using a variety of techniques known as gene therapy. In this instance, genes are injected to treat an illness into a person’s cells and tissues. Statement 1 is correct: Genetic modifications can be made to germ cells (sperm or eggs) of prospective parents. Techniques like CRISPR/Cas9 allow for precise editing of DNA in these cells, potentially preventing the transmission of genetic diseases to offspring. Statement 2 is correct: Genome editing technologies, such as CRISPR/Cas9, allow scientists to precisely modify DNA at the early embryonic stage to correct genetic defects. This approach, called germline editing, involves altering the genome of an embryo at its earliest stage of development, ensuring that all cells in the resulting organism carry the change. These genetic modifications are heritable, meaning the

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