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A drug becomes ineffective when it decomposes to 50 % its concentration. If 16 mg of said drug becomes 4 mg in 12 months…

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A drug becomes ineffective when it decomposes to 50 % its concentration. If 16 mg of said drug becomes 4 mg in 12 months, find the time in which drug becomes ineffective given that decomposition of drug follows first order kinetics.

Memory Based Question 29/Jan/25 Evening shift

a

6 months

b

3 months

c

2 months

d

12 months

✓ Correct answer: a)

6 months

Explanation

The drug follows first-order kinetics. Using the formula \(k=\frac{2.303}{t}\log ⁡\frac{[{A}_{0}]}{[A]}\) , we find \(k=0.1156\) month−1. The half-life is \({t}_{1\mathrm{/}2}=\frac{0.693}{k}=6\) months.

Correct answer: A (6 months).

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