A drug becomes ineffective when it decomposes to 50 % its concentration. If 16 mg of said drug becomes 4 mg in 12 months…
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A drug becomes ineffective when it decomposes to 50 % its concentration. If 16 mg of said drug becomes 4 mg in 12 months, find the time in which drug becomes ineffective given that decomposition of drug follows first order kinetics.
Memory Based Question 29/Jan/25 Evening shift
✓ Correct answer: a)
6 months
Explanation
The drug follows first-order kinetics. Using the formula \(k=\frac{2.303}{t}\log \frac{[{A}_{0}]}{[A]}\) , we find \(k=0.1156\) month−1. The half-life is \({t}_{1\mathrm{/}2}=\frac{0.693}{k}=6\) months.
Correct answer: A (6 months).
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